Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673147 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EHPGDCYP1A2GLA | |
| SCHEMBL1240376 | 0.76 | KDM4E (0.49) | ALDH1A1KDM4EHPGDGLACYP2C19 | |
| SCHEMBL30901263 | 0.76 | KDM4E (0.49) | ALDH1A1KDM4EHPGDGLACYP2C19 | |
| SCHEMBL10235160 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDCYP1A2GLA | |
| SCHEMBL19538924 | 0.74 | GPR3 (0.56) | ALDH1A1KDM4EHPGDCYP1A2GLA | |
| SCHEMBL21939787 | 0.73 | KDM4E (0.55) | ALDH1A1KDM4EHPGDGLACYP2C19 | |
| SCHEMBL30835552 | 0.73 | KDM4E (0.55) | ALDH1A1KDM4EHPGDGLACYP2C19 | |
| SCHEMBL19539157 | 0.73 | KDM4E (0.60) | ALDH1A1KDM4EHPGDCYP1A2GLA | |
| SCHEMBL15876642 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGLASMN1; SMN2 | |
| SCHEMBL31018139 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884204-B2 | such as (2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-3-quinolinyl)phenyl]propionic acid, used for the teratment of inflammatory diseases, arthritis, inflammatory bowel diseases, lupus, multiple syndrome, asthma, psoriasis, allergies, diabetes and cardiovascular diseases | AJINOMOTO CO., INC. (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20080280909-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2008-11-13 | — | — | US | disclosed |
| US-7250516-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-20040235848-A1 | For therapy of inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic erythematodes, multiple sclerosis, Sjogren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis | AJINOMOTO CO., INC. (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1454898-A1 | NOVEL PHENYLALANINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2004-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235848-A1 | For therapy of inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic erythematodes, multiple sclerosis, Sjogren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis | VCAM1, ICAM1, CD40 | ALDH1A1 1526/4885KDM4E 880/4885HPGD 3829/4885 |
| US-20080280909-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | ALDH1A1 1238/4885KDM4E 268/4885HPGD 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.