Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607893 | 0.90 | PSMB8 (0.35) | PSMB8PSMB5MGLL | |
| SCHEMBL34437 | 0.90 | PSMB8 (0.34) | PSMB8PSMB5MGLL | |
| SCHEMBL2263421 | 0.89 | MGLL (0.35) | PSMB8PSMB5MGLL | |
| SCHEMBL25818845 | 0.88 | PSMB8 (0.34) | PSMB8PSMB5MGLL | |
| SCHEMBL15760633 | 0.87 | PSMB8 (0.34) | PSMB8PSMB5MGLL | |
| Ethylene Glycol SCHEMBL999673 | 0.86 | PSMB8 (0.36) | PSMB8PSMB5MGLL | |
| SCHEMBL16130614 | 0.84 | SMN1; SMN2 (0.36) | PSMB8PSMB5MGLL | |
| SCHEMBL43576 | 0.84 | PSMB8 (0.35) | PSMB8PSMB5MGLL | |
| SCHEMBL16303081 | 0.83 | SMN1; SMN2 (0.38) | PSMB8PSMB5 | |
| SCHEMBL7877323 | 0.83 | SMN1; SMN2 (0.38) | PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-8449872-B2 | Polymer conjugates of nesiritide peptides | NEKTAR THERAPEUTICS (US) | 2013-05-28 | — | — | US | disclosed |
| US-20130059360-A1 | POLYMER-BASED COMPOSITIONS AND CONJUGATES OF ANTIMICROBIAL AGENTS | NEKTAR THERAPEUTICS (US) | 2013-03-07 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
| US-20110165111-A1 | POLYMER CONJUGATES OF NESIRITIDE PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165111-A1 | POLYMER CONJUGATES OF NESIRITIDE PEPTIDES | NGLY1, IAPP, NPSR1 | PSMB8 2402/4885PSMB5 1228/4885MGLL 4553/4885 |
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | IAPP, GCG, INSR | PSMB8 1669/4885PSMB5 981/4885MGLL 3059/4885 |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | CALCR, CALCB, CALCA | PSMB8 3488/4885PSMB5 2931/4885MGLL 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.