Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2610137 | 0.83 | L3MBTL1 (0.42) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1789913 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTNPC1 | |
| SCHEMBL5317124 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTNPC1 | |
| SCHEMBL9777731 | 0.79 | KDM4E (0.42) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28398612 | 0.75 | ALDH1A1 (0.39) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL13111217 | 0.72 | MEN1 (0.31) | LMNARAB9A | |
| SCHEMBL30536243 | 0.72 | ALDH1A1 (0.39) | ALDH1A1GAALMNAHTTPKM | |
| SCHEMBL2610138 | 0.72 | TRPA1 (0.42) | ALDH1A1GAAHTTNPC1RAB9A | |
| SCHEMBL3295316 | 0.72 | TRPA1 (0.42) | ALDH1A1GAAHTTNPC1RAB9A | |
| SCHEMBL7932437 | 0.71 | ALDH1A1 (0.33) | ALDH1A1GAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160136286-A1 | DRUG DELIVERY COMPOSITION | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-19 | — | — | US | disclosed |
| US-20160136286-A1 | DRUG DELIVERY COMPOSITION | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-19 | — | — | US | disclosed |
| US-9271928-B2 | Drug delivery composition | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-03-01 | — | — | US | disclosed |
| US-9271928-B2 | Drug delivery composition | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-03-01 | — | — | US | disclosed |
| US-20110165114-A1 | DRUG DELIVERY COMPOSITION | QUEEN'S UNIVERSITY OF BELFAST, THE (GB) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110165114-A1 | DRUG DELIVERY COMPOSITION | ECPAS, ABCB11, ABCB1 | ALDH1A1 1965/4885GAA 3879/4885PDE4A 2551/4885 |
| US-20160136286-A1 | DRUG DELIVERY COMPOSITION | ECPAS, ABCB11, ABCB1 | ALDH1A1 1965/4885GAA 3879/4885PDE4A 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.