Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381400 | 1.00 | PLD1 (0.44) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| SCHEMBL12414489 | 1.00 | PLD1 (0.44) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| Hydrochloric Acid SCHEMBL28320678 | 0.98 | PLD1 (0.43) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| Hydrochloric Acid SCHEMBL28320684 | 0.98 | PLD1 (0.43) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| Hydrochloric Acid SCHEMBL28320677 | 0.98 | PLD1 (0.43) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| SCHEMBL27110100 | 0.89 | PLD1 (0.37) | PLD1DPP4PIK3CDCHRNB2CHRNA3 | |
| Trifluoroacetic Acid SCHEMBL28058910 | 0.89 | DPP4 (0.40) | PLD1DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL28320668 | 0.89 | DPP4 (0.40) | PLD1DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL28058919 | 0.89 | DPP4 (0.40) | PLD1DPP4DPP7 | |
| SCHEMBL12583222 | 0.87 | PLD1 (0.43) | PLD1DPP4DPP7ENPP2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398812-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | US | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| US-20230108325-A1 | Pyrazolopyridine Derivatives and Uses thereof | NOVARTIS AG (CH) | 2023-04-06 | — | — | US | disclosed |
| CN-114555593-A | 4-substituted indole and indazole sulfonamide derivatives as PARG inhibitors | 伊迪亚生物科学有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-8293729-B2 | Compounds, pharmaceutical composition and methods relating thereto | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-23 | — | — | US | disclosed |
| US-20110166116-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | HBZ, ZFX, WIZ | PLD1 4236/4885DPP4 3398/4885PIK3CD 3833/4885 |
| US-20240398812-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | MCOLN1, PKD2, MCOLN3 | PLD1 1059/4885DPP4 4174/4885PIK3CD 886/4885 |
| US-20230108325-A1 | Pyrazolopyridine Derivatives and Uses thereof | HBZ, ZFX, WIZ | PLD1 4236/4885DPP4 3398/4885PIK3CD 3833/4885 |
| US-20110166116-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | MC2R, REN, CYP11B2 | PLD1 1266/4885DPP4 340/4885PIK3CD 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.