SCHEMBL12415342

SCHEMBL12415342

Ic1c2ccccc2c(-c2ccc(-c3ccccc3)cc2)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.43
ESR2 Q92731 5/20 0.43
ACHE P22303 4/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 2/20 0.39
MAPT P10636 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
CYP3A4 P08684 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EGFR P00533 1/20 0.35
PTGS2 P35354 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295908 0.95 ESR1 (0.46) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL27919608 0.87 ALDH1A1 (0.56) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL21435722 0.87 ALDH1A1 (0.56) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL21435740 0.87 ALDH1A1 (0.56) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL27367260 0.87 ALDH1A1 (0.56) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL5448953 0.85 ALDH1A1 (0.53) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL12415341 0.85 MAOA (0.40) ESR1ESR2ACHEALDH1A1
SCHEMBL30309416 0.84 ACHE (0.54) ESR1ESR2ACHEALDH1A1MAPK1
SCHEMBL5572261 0.84 ACHE (0.54) ESR1ESR2ACHEALDH1A1MAPK1
Biphenyl SCHEMBL27941416 0.84 ALDH1A1 (0.60) ESR1ESR2ACHEALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-27 US disclosed
US-11569449-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2023-01-31 US disclosed
US-11342512-B2 Compounds for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2022-05-24 US disclosed
US-20220020925-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-01-20 US disclosed
US-20210395233-A1 NEW COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-12-23 US disclosed
US-11139437-B2 Compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2021-10-05 US disclosed
US-20210066599-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-03-04 US disclosed
US-20210062078-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-03-04 US disclosed
US-20200098994-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-03-26 US disclosed
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-11-21 US disclosed
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 US disclosed
US-20190214579-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-8283855-B2 Method for synthesis of anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 US disclosed
US-8283855-B2 Method for synthesis of anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-09 US disclosed
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-07-14 US disclosed
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11139437-B2 Compound and organic electroluminescence device RIF1, OR10J3, LEF1 ESR1 71/4885ESR2 221/4885ACHE 1926/4885
US-20210066599-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE RPS19, RPL18, RPL19 ESR1 187/4885ESR2 181/4885ACHE 1877/4885
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L ESR1 208/4885ESR2 397/4885ACHE 670/4885
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device RER1, RPS19, RPL19 ESR1 5/4885ESR2 13/4885ACHE 2650/4885
US-20110172441-A1 METHOD FOR SYNTHESIS OF ANTHRACENE DERIVATIVE CYP1A1, AHR, CYP2C9 ESR1 1738/4885ESR2 1418/4885ACHE 954/4885
US-20210395233-A1 NEW COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AHR, UQCRB, AOC2 ESR1 36/4885ESR2 28/4885ACHE 2559/4885
US-20200098994-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, NOM1, RIF1 ESR1 120/4885ESR2 518/4885ACHE 1105/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 ESR1 445/4885ESR2 1111/4885ACHE 2762/4885
US-11342512-B2 Compounds for organic electroluminescence device RPS19, RPL19, RPL18 ESR1 198/4885ESR2 98/4885ACHE 2411/4885
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND OR10J3, OR51E2, TRPC6 ESR1 16/4885ESR2 66/4885ACHE 3088/4885
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L ESR1 208/4885ESR2 397/4885ACHE 670/4885
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, EPCAM, TMEM109 ESR1 8/4885ESR2 73/4885ACHE 1420/4885
US-20190214579-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, RIF1, OR10J3 ESR1 266/4885ESR2 523/4885ACHE 1779/4885
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND KCNN4, OR10J3, KCNN2 ESR1 8/4885ESR2 43/4885ACHE 3254/4885
US-11569449-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L ESR1 208/4885ESR2 397/4885ACHE 670/4885
US-20220020925-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE RPS19, RPL18, RPL19 ESR1 187/4885ESR2 181/4885ACHE 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.