Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12419011 | 0.85 | NPC1 (0.41) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL12414159 | 0.79 | MMP13 (0.61) | MMP13SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL12419012 | 0.77 | CYP4F2 (0.41) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL12419087 | 0.77 | GAA (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL19645264 | 0.76 | MMP13 (0.62) | MMP13SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL620074 | 0.73 | POLB (0.66) | MMP13CA12CA1CA2CA9 | |
| SCHEMBL6024439 | 0.71 | NPC1 (0.75) | MMP13SMN1; SMN2CA1CA2NPC1 | |
| SCHEMBL14753642 | 0.69 | POLB (0.62) | MMP13SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL12913509 | 0.69 | MAOB (0.70) | MMP13CA12CA1CA2CA9 | |
| SCHEMBL853629 | 0.69 | KDM4E (0.61) | MMP13CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171166-A1 | POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES | NEKTAR THERAPEUTICS | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171166-A1 | POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES | SOST, PTMS, ALPP | MMP13 41/4885SMN1; SMN2 3235/4885CA12 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.