SCHEMBL12419182

SCHEMBL12419182

CCC(C)C(=O)Oc1c2ccccc2c(Br)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.38
NCEH1 Q6PIU2 3/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.35
LMNA P02545 3/20 0.35
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP2C9 P11712 2/20 0.34
THRB P10828 1/20 0.34
CYP2C19 P33261 1/20 0.34
FFAR1 O14842 1/20 0.34
TSHR P16473 2/20 0.33
TACR3 P29371 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28301504 0.92 L3MBTL1 (0.40) HSD17B10MAPTSMN1; SMN2L3MBTL1LMNA
SCHEMBL12419181 0.86 L3MBTL1 (0.37) HSD17B10MAPTSMN1; SMN2L3MBTL1LMNA
SCHEMBL8738725 0.86 ALDH1A1 (0.39) HSD17B10MAPTL3MBTL1LMNAKDM4E
SCHEMBL12419186 0.84 LMNA (0.37) NCEH1MAPTSMN1; SMN2NPC1L3MBTL1
SCHEMBL12419174 0.81 KDM4E (0.40) HSD17B10MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL12385764 0.77 GAA (0.38) HSD17B10MAPTSMN1; SMN2LMNAKDM4E
SCHEMBL15447053 0.77 LMNA (0.45) NCEH1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL15447052 0.76 HTT (0.40) MAPTL3MBTL1LMNAKDM4EKMT2A
SCHEMBL15796988 0.76 FFAR1 (0.39) MAPTSMN1; SMN2L3MBTL1LMNAKDM4E
SCHEMBL8738223 0.76 LCK (0.37) HSD17B10MAPTNPC1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180180998-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-28 US disclosed
US-20180039175-A1 NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-08 US disclosed
US-9740098-B2 Chemically amplified negative resist composition using novel onium salt and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-22 US disclosed
US-9604921-B2 Sulfonium salt, resist composition and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-28 US disclosed
US-20160299428-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION USING NOVEL ONIUM SALT AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-13 US disclosed
US-9436083-B2 Chemically-amplified negative resist composition and resist patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-06 US disclosed
US-9329476-B2 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-03 US disclosed
US-20160090355-A1 SULFONIUM SALT, RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-03-31 US disclosed
US-20150268556-A1 CHEMICALLY-AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-09-24 US disclosed
US-20150198877-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-16 US disclosed
US-20110171579-A1 NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180180998-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SLC11A2, POLR2B, POLI HSD17B10 4284/4885NCEH1 4804/4885MAPT 3178/4885
US-20160090355-A1 SULFONIUM SALT, RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS ETV6, ETV1, EIF2B3 HSD17B10 1674/4885NCEH1 4239/4885MAPT 4438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.