SCHEMBL8738725

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28301504	0.93	L3MBTL1 (0.40)	ALDH1A1GAAKDM4EHSD17B10HTT
	SCHEMBL12385764	0.90	GAA (0.38)	ALDH1A1GAAHPGDKDM4EHSD17B10
	SCHEMBL12419181	0.87	L3MBTL1 (0.37)	ALDH1A1GAAHPGDKDM4EHSD17B10
	SCHEMBL12419186	0.86	LMNA (0.37)	ALDH1A1KDM4EHTTLMNAMAPT
	SCHEMBL12419182	0.86	HSD17B10 (0.38)	ALDH1A1KDM4EHSD17B10LMNAMAPT
	SCHEMBL12419174	0.83	KDM4E (0.40)	ALDH1A1GAAHPGDKDM4EHSD17B10
	SCHEMBL18671982	0.83	ALDH1A1 (0.38)	ALDH1A1GAAHPGDKDM4EHSD17B10
	SCHEMBL8738223	0.82	LCK (0.37)	ALDH1A1GAAKDM4EHSD17B10HTT
	SCHEMBL15447053	0.78	LMNA (0.45)	ALDH1A1KDM4ELMNAMAPTL3MBTL1
	SCHEMBL15447052	0.77	HTT (0.40)	ALDH1A1HPGDKDM4EHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.