SCHEMBL12419367

SCHEMBL12419367

CB(C)c1ccc(CC2OCCCO2)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419357 0.93 LPL (0.32) LPLLIPG
SCHEMBL1773236 0.76 MEN1 (0.41) SMN1; SMN2
Methyl Alcohol SCHEMBL28286625 0.76 ALDH1A1 (0.39) SMN1; SMN2
SCHEMBL25585 0.75 ALDH1A1 (0.41) SMN1; SMN2
SCHEMBL2882191 0.74 CA2 (0.43) SMN1; SMN2
SCHEMBL27595482 0.71 ALDH1A1 (0.46) SMN1; SMN2L3MBTL1
SCHEMBL448797 0.71 ALDH1A1 (0.41) SMN1; SMN2
SCHEMBL29911017 0.71 LPL (0.40) SMN1; SMN2LPLLIPG
SCHEMBL21154704 0.71 ALDH1A1 (0.40) SMN1; SMN2L3MBTL1
SCHEMBL3950950 0.69 ALDH1A1 (0.40) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150368278-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2015-12-24 US disclosed
US-8957049-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2015-02-17 US disclosed
US-20110172186-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172186-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 SMN1; SMN2 3053/4885L3MBTL1 4079/4885LPL 116/4885
US-20150368278-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 SMN1; SMN2 3053/4885L3MBTL1 4079/4885LPL 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.