Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090488 | 0.75 | TSHR (0.40) | ERN1RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL514306 | 0.74 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL4552467 | 0.74 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL146988 | 0.73 | CES2 (0.42) | ERN1CES2CES1 | |
| SCHEMBL29823308 | 0.73 | ERN1 (0.59) | ERN1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL18190444 | 0.73 | ERN1 (0.59) | ERN1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2092487 | 0.72 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2TSHRPABPC1 | |
| SCHEMBL3333781 | 0.72 | TSHR (0.38) | ERN1RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL7189586 | 0.69 | TSHR (0.43) | RAB9ANPC1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL20880608 | 0.68 | GAA (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998412-B2 | Ophthalmic device comprising a holographic sensor | SMART HOLOGRAMS LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |