SCHEMBL7189586

SCHEMBL7189586

O=CNc1ccccc1B(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ALDH1A1 P00352 2/20 0.41
PABPC1 P11940 1/20 0.38
ENPP2 Q13822 1/20 0.38
KDM5A P29375 2/20 0.34
RXFP1 Q9HBX9 1/20 0.34
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LIPG Q9Y5X9 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1798448 0.85 PABPC1 (0.41) TSHRALDH1A1PABPC1ENPP2KDM5A
SCHEMBL30527294 0.77 ALDH1A1 (0.57) TSHRALDH1A1PABPC1KDM5ARXFP1
SCHEMBL8763290 0.77 ALDH1A1 (0.57) TSHRALDH1A1PABPC1KDM5ARXFP1
SCHEMBL9893708 0.76 TSHR (0.36) TSHRALDH1A1
SCHEMBL29469192 0.73 POLB (0.44) TSHRALDH1A1PABPC1ENPP2RECQL
SCHEMBL3198768 0.73 POLB (0.44) TSHRALDH1A1PABPC1ENPP2RECQL
SCHEMBL14822549 0.73 ENPP2 (0.43) ALDH1A1ENPP2RECQLSMN1; SMN2LIPG
SCHEMBL1331721 0.71 LMNA (0.55) TSHRALDH1A1PABPC1KDM5ASMN1; SMN2
SCHEMBL6524293 0.71 ENPP2 (0.41) ALDH1A1ENPP2RECQLSMN1; SMN2LIPG
SCHEMBL1939410 0.71 GAA (0.50) TSHRALDH1A1PABPC1KDM5ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-211384996-U Formamido phenyl boric acid preparation reaction kettle device 武汉利昌医药科技有限公司 2020-09-01 CN claimed
CN-211177765-U Drying device for producing and preparing formamido phenyl boric acid 武汉利昌医药科技有限公司 2020-08-04 CN claimed
CN-117342907-A Method for preparing phenol by hydroxylation reaction of boric acid derivative in air under no-alkali condition without light catalyst 江西科技师范大学 2024-01-05 CN disclosed
CN-211384996-U Formamido phenyl boric acid preparation reaction kettle device 武汉利昌医药科技有限公司 2020-09-01 CN disclosed
CN-211177765-U Drying device for producing and preparing formamido phenyl boric acid 武汉利昌医药科技有限公司 2020-08-04 CN disclosed
US-20180125798-A1 Compounds and Methods for Modulating Serotonin Receptors in the Periphery NORTHEASTERN UNIVERSITY 2018-05-10 US disclosed
US-7998412-B2 Ophthalmic device comprising a holographic sensor SMART HOLOGRAMS LIMITED (GB) 2011-08-16 US disclosed
US-20090021697-A1 Ophthalmic Device Comprising a Holographic Sensor SMART HOLOGRAMS LIMITED (GB) 2009-01-22 US disclosed
US-20030220516-A1 Process for the preparation of substituted phenylboronic acids CLARIANT GMBH 2003-11-27 US disclosed
US-6576789-B1 Process for the preparation of substituted phenylboronic acids CLARIANT GMBH (DE) 2003-06-10 US disclosed
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180125798-A1 Compounds and Methods for Modulating Serotonin Receptors in the Periphery HTR5A, HTR3A, HTR1A TSHR 364/4885ALDH1A1 3040/4885PABPC1 3056/4885
US-20030220516-A1 Process for the preparation of substituted phenylboronic acids ME1, KCNH1, CA6 TSHR 3363/4885ALDH1A1 383/4885PABPC1 1682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.