Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090488 | 0.82 | TSHR (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL8763290 | 0.82 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL30527294 | 0.82 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL3333781 | 0.79 | TSHR (0.38) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL2092487 | 0.79 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL27834680 | 0.77 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL3166136 | 0.76 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL27551601 | 0.76 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL12420965 | 0.74 | ERN1 (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL8967636 | 0.74 | PABPC1 (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598766-A | Method for preparing C-7-formamido substituted p-methylene quinone compound | 湖南理工学院 | 2024-09-06 | — | — | CN | claimed |
| CN-111662185-B | Synthesis method of N-methyl o-fluoroaniline | 江苏富鼎化学有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-113429297-A | Method for synthesizing N-methyl o-fluoroaniline by one-pot method | 江西汇和化工有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-111662185-A | Synthesis method of N-methyl o-fluoroaniline | 江苏富鼎化学有限公司 | 2020-09-15 | — | — | CN | claimed |
| EP-2513054-B1 | BICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF DPP-1 | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-09 | — | — | EP | claimed |
| US-20110046368-A1 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | IVASHCHENKO ANDREY ALEXANDROVICH | 2011-02-24 | — | — | US | claimed |
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | claimed |
| US-20050227974-A9 | Aminoalkyl-substituted aryl compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2005-10-13 | — | — | US | claimed |
| EP-1525194-A1 | AMINOALKYL-SUBSTITUTED ARYL COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | Euro-Celtique S.A. (LU) | 2005-04-27 | — | — | EP | claimed |
| US-20040116415-A1 | Aminoalkyl-substituted aryl compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2004-06-17 | — | — | US | claimed |
| WO-2004013114-A1 | AMINOALKYL-SUBSTITUTED ARYL COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2004-02-12 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | claimed |
| CN-118598766-A | Method for preparing C-7-formamido substituted p-methylene quinone compound | 湖南理工学院 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024071216-A1 | PYRAZOLE COMPOUND AND PEST CONTROL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 三井化学クロップ＆ライフソリューション株式会社 | 2024-04-04 | — | — | WO | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-4272551-A | N-Sulfenylated formanilides useful as fungicides and bactericides | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-09 | — | — | US | disclosed |
| EP-0008731-B1 | N-SULFENYL FORMANILIDES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | disclosed |
| EP-0008731-A1 | N-sulfenyl formanilides, their preparation and their use as fungicides | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227974-A9 | Aminoalkyl-substituted aryl compounds and their use as sodium channel blockers | KCNN3, CACNA1S, CACNA1C | RAB9A 3212/4885SMN1; SMN2 107/4885NPC1 1139/4885 |
| US-20110046368-A1 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | HTR6, HTR1A, HTR3B | RAB9A 4005/4885SMN1; SMN2 1856/4885NPC1 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.