SCHEMBL12422829

SCHEMBL12422829

CC1(C)CC(CN(C=C(c2ccccc2)c2ccccc2)CC2CC(C)(C)OC(C)(C)C2)CC(C)(C)O1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.32
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422828 0.74 HDAC1 (0.42)
SCHEMBL12422831 0.69 CYP19A1 (0.41) SIGMAR1
SCHEMBL12422795 0.67 ALDH1A1 (0.40) SIGMAR1
SCHEMBL12422833 0.67 HPGD (0.49)
SCHEMBL28005546 0.64 SIGMAR1 (0.38) SIGMAR1
SCHEMBL28005578 0.63 AOC3 (0.41) SIGMAR1
SCHEMBL12422791 0.62 G6PC1 (0.43) SIGMAR1
SCHEMBL12377628 0.62 ALDH1A1 (0.36) SIGMAR1
SCHEMBL8773436 0.61 CYP1A2 (0.43)
SCHEMBL28081835 0.60 RECQL (0.47) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SLC1A2, SLC1A1, SLC18A1 CHRM3 430/4885SIGMAR1 3652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.