SCHEMBL12424873

SCHEMBL12424873

O=C1NC(c2cc(F)cc(F)c2)=C2C(=O)NC(c3cc(F)cc(F)c3)=C12

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.35
NOTUM Q6P988 1/20 0.32
GRM5 P41594 1/20 0.32
NISCH Q9Y2I1 1/20 0.31
PGR P06401 2/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424956 0.87 DAPK3 (0.32)
SCHEMBL12425010 0.87 NOTUM (0.41) NOTUMGRM5PGR
SCHEMBL12424928 0.83 RXRA (0.41) NOTUMPGRPTGS1
SCHEMBL12424859 0.80 CES2 (0.33) TGM2CES2CES1PTGS2
SCHEMBL12424864 0.79 NOTUM (0.44) NOTUMGRM5PGR
SCHEMBL12424865 0.77 MAPT (0.41) NOTUMGRM5PTGS1
SCHEMBL12424896 0.76 TGM2 (0.42) TGM2CES2CES1
SCHEMBL12424993 0.75 MAPT (0.37) GRM5PGR
SCHEMBL12425007 0.74 NOTUM (0.37) NOTUMGRM5PGR
SCHEMBL12424911 0.73 CES1 (0.36) PGRCES1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed