Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | PNLIP | P16233 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427905 | 0.83 | MAPT (0.73) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL27347841 | 0.82 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL30307513 | 0.82 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL22192202 | 0.80 | MAPT (0.61) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL19077945 | 0.79 | ALOX15 (0.68) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL18327174 | 0.79 | LMNA (0.89) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL5656688 | 0.78 | LMNA (0.64) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL12427902 | 0.78 | NPC1 (0.60) | MEN1KMT2ANPC1RAB9ALMNA | |
| Salicylanilide SCHEMBL14051034 | 0.77 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9ALMNA | |
| Salicylanilide SCHEMBL152221 | 0.77 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246792-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2014-08-13 | — | — | EP | disclosed |
| EP-1246792-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2014-08-13 | — | — | EP | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-7151191-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-12-19 | — | — | US | disclosed |
| EP-1246792-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-02-16 | — | — | EP | disclosed |
| US-20030149296-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-08-07 | — | — | US | disclosed |
| EP-1246792-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051454-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | MEN1 1531/4885KMT2A 4537/4885NPC1 52/4885 |
| US-20030149296-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | MEN1 1531/4885KMT2A 4537/4885NPC1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.