SCHEMBL12433462

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12227987	0.72	CYP1A2 (0.52)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL12433465	0.72	CYP2A6 (0.41)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL597701	0.72	CYP1A2 (0.60)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL10153933	0.72	ALDH1A1 (0.42)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL8237013	0.72	NFE2L2 (0.39)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL18078259	0.72	MAOA (0.43)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL12433463	0.71	ALDH1A1 (0.53)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL607927	0.70	CYP1A2 (0.71)	CYP1A2CYP2A6ALDH1A1LMNAGAA
	SCHEMBL1990091	0.69	ACHE (0.56)	ALDH1A1LMNAGAAHPGDMAPT
	SCHEMBL21788093	0.69	CYP2A6 (0.38)	CYP1A2CYP2A6ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.