Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193788 | 0.77 | L3MBTL1 (0.56) | SLC6A9L3MBTL1POLBMAOBKDM4E | |
| SCHEMBL12434732 | 0.77 | L3MBTL1 (0.56) | SLC6A9L3MBTL1POLBMAOBKDM4E | |
| SCHEMBL12434731 | 0.77 | SLC6A9 (0.41) | SLC6A9L3MBTL1POLBHRH3KDM4E | |
| SCHEMBL10832824 | 0.74 | MAPT (0.45) | L3MBTL1OPRM1HRH3KDM4EALDH1A1 | |
| SCHEMBL10831602 | 0.73 | MAPT (0.44) | L3MBTL1CHRM2CHRM1DRD1SLC6A2 | |
| SCHEMBL3082979 | 0.72 | GAA (0.71) | MAOBOPRM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1205842 | 0.72 | GAA (0.71) | MAOBOPRM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL243405 | 0.72 | LMNA (0.47) | L3MBTL1POLBKDM4EALDH1A1GLA | |
| SCHEMBL6979453 | 0.72 | GAA (0.71) | MAOBOPRM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13217608 | 0.72 | HTR2A (0.41) | L3MBTL1POLBKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2353714-A1 | ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |