Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12439879 | 0.88 | KMO (0.46) | KMOSCN9ASCN5AEDNRBEDNRA | |
| SCHEMBL12439856 | 0.84 | TGFBR1 (0.40) | KMOSCN9AMAPK14ALOX5TGFBR1 | |
| SCHEMBL1935092 | 0.83 | TGFBR1 (0.47) | TRPA1KMOSCN9ATGFBR1 | |
| SCHEMBL12439875 | 0.83 | KMO (0.44) | KMOMAPK14ALOX5KDRMAPKAPK2 | |
| SCHEMBL12439886 | 0.82 | TRPA1 (0.41) | TRPA1KMOSCN9AMAPK14DHODH | |
| SCHEMBL1936339 | 0.80 | TRPA1 (0.44) | TRPA1KMOSCN9AMAPK14SCN5A | |
| SCHEMBL1935751 | 0.79 | NOTUM (0.45) | KMOMAPK14TGFBR1MAPK13MAPK9 | |
| SCHEMBL1935063 | 0.79 | DHODH (0.47) | KMOMAPK14DHODHALOX5TGFBR1 | |
| SCHEMBL12439881 | 0.79 | TRPA1 (0.40) | TRPA1KMODHODHALOX5MAPKAPK2 | |
| SCHEMBL12439874 | 0.79 | TRPA1 (0.40) | TRPA1KMOSCN9ADHODHALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | TRPA1 324/4885KMO 632/4885SCN9A 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.