Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.35 |
| ▸ | EDNRB | P24530 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12439881 | 0.91 | TRPA1 (0.40) | TRPA1KMOALOX5DHODHMAPKAPK2 | |
| SCHEMBL1934821 | 0.89 | MAPKAPK2 (0.40) | KMOTGFBR1MAPKAPK2EDNRBEDNRA | |
| SCHEMBL12439894 | 0.88 | KMO (0.39) | KMOALOX5TGFBR1MAPKAPK2EDNRB | |
| SCHEMBL1935092 | 0.86 | TGFBR1 (0.47) | TRPA1KMOTGFBR1SCN9A | |
| SCHEMBL1935306 | 0.85 | ALDH1A1 (0.40) | KMOTGFBR1MAPKAPK2EDNRBEDNRA | |
| SCHEMBL12439856 | 0.83 | TGFBR1 (0.40) | KMOALOX5TGFBR1MAPKAPK2SCN9A | |
| SCHEMBL1935547 | 0.82 | ALOX5AP (0.40) | KMOTGFBR1MAPKAPK2EDNRBEDNRA | |
| SCHEMBL12439875 | 0.81 | KMO (0.44) | KMOALOX5MAPKAPK2ALDH1A1PDE3B | |
| SCHEMBL12439870 | 0.81 | KMO (0.44) | KMOTGFBR1MAPKAPK2SCN9AKLKB1 | |
| SCHEMBL12514519 | 0.80 | MAPKAPK2 (0.40) | KMOALOX5TGFBR1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | TRPA1 324/4885KMO 632/4885ALOX5 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.