SCHEMBL1243989

SCHEMBL1243989

[O]c1c(Cl)ccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.60
CYP1A2 P05177 4/20 0.52
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
PAX8 Q06710 1/20 0.48
HPRT1 P00492 1/20 0.46
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
MAPT P10636 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 2/20 0.39
CYP3A4 P08684 1/20 0.39
APEX1 P27695 1/20 0.39
MAPK1 P28482 1/20 0.39
PMP22 Q01453 1/20 0.39
TP53 P04637 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2199292 0.80 CYP2A6 (0.43) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL5673224 0.75 CYP2A6 (0.65) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
1,2-Naphthoquinone SCHEMBL2146624 0.75 ALDH1A1 (0.55) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL449348 0.75 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL7478320 0.74 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Ammonia Solution, Strong SCHEMBL11476794 0.73 CYP2A6 (0.95) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL5610395 0.73 CYP2A6 (0.45) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL7483792 0.71 CYP2A6 (0.60) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL1402510 0.71 TSHR (0.60) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL4630201 0.71 ALDH1A1 (0.52) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
US-4246172-A FOR DYEING TEXTILES SUCH AS POLYACRYLONITRILE, AND ACID MODIFIED POLYESTERS AND POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US claimed
EP-2123695-B1 METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, RESIN, AND USE OF THE RESIN MITSUI CHEMICALS INC (JP) 2021-06-23 EP disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US disclosed
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-20180029968-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD OF COMPOUND OR RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-01 US disclosed
EP-3257835-A1 COMPOUND, RESIN, LITHOGRAPHY UNDERLAYER FILM FORMING MATERIAL, LITHOGRAPHY UNDERLAYER FILM FORMING COMPOSITION, LITHOGRAPHY UNDERLAYER FILM, METHOD FOR FORMING RESIST PATTERN, METHOD FOR FORMING CIRCUIT PATTERN, AND METHOD FOR PURIFYING COMPOUND OR RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2017-12-20 EP disclosed
US-20170349564-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD, AND PURIFICATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-12-07 US disclosed
EP-3239141-A1 COMPOUND, RESIN, UNDERLAYER FILM FORMING MATERIAL FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD AND PURIFICATION METHOD Mitsubishi Gas Chemical Company, Inc. (JP) 2017-11-01 EP disclosed
EP-0520146-A1 Process for preparing a thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1992-12-30 EP disclosed
US-5159008-A High viscosity polyphenylene ether, low viscosity polyphenylen ether, polyamide unsaturated polar compound, and mineral filles and-or glass fibers MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-10-27 US disclosed
US-5091473-A Polyamide, polyphenylene ether, block polymer, unsaturated acid or anhydride dispension, hydrogenated impact strength, rigidity, heat resistance MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-02-25 US disclosed
EP-0454156-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1991-10-30 EP disclosed
US-5026787-A Blends of polyphenylene ether, polyamides, unsaturated compounds MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-06-25 US disclosed
US-5001181-A polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1991-03-19 US disclosed
EP-0381056-A2 Impact resistant thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1990-08-08 EP disclosed
EP-0357065-A2 Resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-03-07 EP disclosed
US-4701565-A REACTING ALCOHOL WITH ORGANIC SULFONYL HALIDE TO FORM SULFONATE, REACTING SULFONATE WITH A PHENOL FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 CYP2A6 375/4885CYP1A2 360/4885ALDH1A1 151/4885
US-20170349564-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, PATTERN FORMING METHOD, AND PURIFICATION METHOD ASH2L, MLLT1, FRG1 CYP2A6 1906/4885CYP1A2 1815/4885ALDH1A1 1912/4885
US-20180029968-A1 COMPOUND, RESIN, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, UNDERLAYER FILM FOR LITHOGRAPHY, RESIST PATTERN FORMING METHOD, CIRCUIT PATTERN FORMING METHOD, AND PURIFICATION METHOD OF COMPOUND OR RESIN PRMT9, ARGLU1, MLLT1 CYP2A6 2371/4885CYP1A2 1768/4885ALDH1A1 1309/4885
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method ASH2L, MLLT1, FRG1 CYP2A6 1906/4885CYP1A2 1815/4885ALDH1A1 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.