SCHEMBL12440256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19791418	0.87	SLC6A4 (0.36)	WNT1ROCK1CYP3A4CLK2CLK3
	SCHEMBL12440260	0.86	WNT1 (0.46)	WNT1CLK2CLK3DYRK1ALTA4H
	SCHEMBL13834700	0.84	PRKCZ (0.40)	WNT1CLK2CLK3DYRK1APIM1
	SCHEMBL12440253	0.83	WNT1 (0.48)	WNT1BMPR1BACVRL1ACVR1BMPR1A
	SCHEMBL12441219	0.79	ACHE (0.44)	WNT1BMPR1BACVRL1ACVR1BMPR1A
	SCHEMBL19791678	0.78	ACP1 (0.41)	WNT1CLK2CLK3DYRK1AHCAR2
	SCHEMBL13834312	0.78	RPS6KA3 (0.43)	SYKROCK1CLK2CLK3DYRK1A
	SCHEMBL12440274	0.77	ACHE (0.46)	ACVRL1ACVR1BMPR1AROCK1KDM4E
	SCHEMBL12439724	0.77	PAICS (0.37)	BMPR1BACVRL1ACVR1BMPR1AMET
	SCHEMBL13834871	0.77	WNT1 (0.44)	WNT1BMPR1BACVRL1ACVR1BMPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.