Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892079 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL863123 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL863284 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL863124 | 0.93 | TSHR (0.43) | TSHRALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL863128 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL863125 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7637824 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2213077 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Diethylene Glycol Diisobutanoate SCHEMBL9561713 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL863288 | 0.91 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030165-A1 | Polycations and Methods of Making and Using Thereof | NATIONAL SCIENCE FOUNDATION | 2018-02-01 | — | — | US | disclosed |
| US-8969532-B2 | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography | NOVO NORDISK A/S (DK) | 2015-03-03 | — | — | US | disclosed |
| US-20110177029-A1 | O-LINKED GLYCOSYLATION USING N-ACETYLGLUCOSAMINYL TRANSFERASES | NOVO NORDISK A/S (DK) | 2011-07-21 | — | — | US | disclosed |
| US-20100075375-A1 | METHODS FOR THE PURIFICATION OF POLYPEPTIDE CONJUGATES | NOVO NORDISK A/S (DK) | 2010-03-25 | — | — | US | disclosed |
| US-20100035299-A1 | METHODS FOR THE PURIFICATION OF POLYPEPTIDE CONJUGATES | NOVO NORDISK A/S (DK) | 2010-02-11 | — | — | US | disclosed |
| US-7514201-B2 | Positive photosensitive composition | FUJIFILM CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20080280818-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NEOSE TECHNOLOGIES, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080274958-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NEOSE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080253992-A1 | Using hydrophobic interaction chromatography to recover therapeutic fusion protein for use in treatment of injuries associated with ischemia, trauma, inflammation and contact with toxic substances | NEOSE TECHNOLOGIES, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080242607-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NEOSE TECHNOLOGIES, INC. (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280818-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NGLY1, OGA, OGT | TSHR 2283/4885ALDH1A1 2918/4885TP53 809/4885 |
| US-20100075375-A1 | METHODS FOR THE PURIFICATION OF POLYPEPTIDE CONJUGATES | PTMS, SIGLEC7, NGLY1 | TSHR 594/4885ALDH1A1 3685/4885TP53 1661/4885 |
| US-20080242607-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NGLY1, OGA, OGT | TSHR 2283/4885ALDH1A1 2918/4885TP53 809/4885 |
| US-20100035299-A1 | METHODS FOR THE PURIFICATION OF POLYPEPTIDE CONJUGATES | PTMS, SIGLEC7, NGLY1 | TSHR 594/4885ALDH1A1 3685/4885TP53 1661/4885 |
| US-20180030165-A1 | Polycations and Methods of Making and Using Thereof | POLI, PARG, PCNA | TSHR 1240/4885ALDH1A1 3567/4885TP53 382/4885 |
| US-20080253992-A1 | Using hydrophobic interaction chromatography to recover therapeutic fusion protein for use in treatment of injuries associated with ischemia, trauma, inflammation and contact with toxic substances | PIGS, CD40, FGB | TSHR 1066/4885ALDH1A1 3695/4885TP53 1631/4885 |
| US-20110177029-A1 | O-LINKED GLYCOSYLATION USING N-ACETYLGLUCOSAMINYL TRANSFERASES | OGT, UGGT1, GALNT6 | TSHR 3863/4885ALDH1A1 1060/4885TP53 2249/4885 |
| US-20080274958-A1 | GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES | NGLY1, OGA, OGT | TSHR 2283/4885ALDH1A1 2918/4885TP53 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.