SCHEMBL12440949

SCHEMBL12440949

CCOc1cc(C)cc(Br)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
L3MBTL1 Q9Y468 4/20 0.47
HPGD P15428 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 1/20 0.43
HSD17B10 Q99714 3/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021620 0.84 MAPT (0.42) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL20005637 0.82 SMN1; SMN2 (0.54) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL16330250 0.80 LMNA (0.41) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL13429875 0.80 LMNA (0.41) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL19732196 0.80 HSD17B10 (0.48) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL10753281 0.78 ALDH1A1 (0.47) MAPTL3MBTL1HPGDLMNAALDH1A1
SCHEMBL19726451 0.77 CRHR1 (0.45) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL15786702 0.77 ACHE (0.48) MAPTL3MBTL1HPGDTSHRALDH1A1
SCHEMBL1126364 0.76 ACHE (0.52) MAPTL3MBTL1HPGDTDP1LMNA
SCHEMBL4697408 0.75 L3MBTL1 (0.75) MAPTL3MBTL1HPGDTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAPT 456/4885L3MBTL1 4308/4885HPGD 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.