Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067699 | 0.91 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308083 | 0.91 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2140974 | 0.91 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25329304 | 0.91 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308082 | 0.91 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12390060 | 0.91 | ALDH1A1 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Water SCHEMBL8124987 | 0.89 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25340359 | 0.89 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL31253447 | 0.89 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL30479553 | 0.88 | MAPT (0.44) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230397605-A1 | METHODS FOR IMPROVING PLANT GROWTH AND CROP YIELD BY USING COMPOUNDS OF TRISULPHIDE OR TETRASULPHIDE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230397605-A1 | METHODS FOR IMPROVING PLANT GROWTH AND CROP YIELD BY USING COMPOUNDS OF TRISULPHIDE OR TETRASULPHIDE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230192604-A1 | METHOD FOR PRODUCING TRISULFIDE COMPOUND OR SELENOTRISULFIDE COMPOUND | KYOWA PHARMA CHEMICAL CO., LTD. (JP) | 2023-06-22 | — | — | US | disclosed |
| US-20230192604-A1 | METHOD FOR PRODUCING TRISULFIDE COMPOUND OR SELENOTRISULFIDE COMPOUND | KYOWA PHARMA CHEMICAL CO., LTD. (JP) | 2023-06-22 | — | — | US | disclosed |
| US-20140228302-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2014-08-14 | — | — | US | disclosed |
| US-8680151-B2 | Compounds, compositions and methods for treating or preventing hypoxic or ischemic injury | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110195945-A1 | Compounds, Compositions and Methods for Treating or Preventing Hypoxic or Ischemic Injury | IKARIA, INC. (US) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195945-A1 | Compounds, Compositions and Methods for Treating or Preventing Hypoxic or Ischemic Injury | HIF1A, HIF1AN, EGLN3 | MAPT 1709/4885KDM4E 3964/4885THRB 3562/4885 |
| US-20140228302-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY | HIF1A, HIF1AN, EGLN3 | MAPT 1709/4885KDM4E 3964/4885THRB 3562/4885 |
| US-20230192604-A1 | METHOD FOR PRODUCING TRISULFIDE COMPOUND OR SELENOTRISULFIDE COMPOUND | TST, SCLY, SQOR | MAPT 2305/4885KDM4E 4319/4885THRB 2110/4885 |
| US-20230397605-A1 | METHODS FOR IMPROVING PLANT GROWTH AND CROP YIELD BY USING COMPOUNDS OF TRISULPHIDE OR TETRASULPHIDE | TST, TXNRD3, STS | MAPT 3738/4885KDM4E 3804/4885THRB 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.