Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | MITF | O75030 | 2/20 | 0.64 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.64 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALPI | P09923 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528684 | 0.88 | SIRT1 (0.80) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5809160 | 0.88 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5809159 | 0.88 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5810164 | 0.88 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8343578 | 0.86 | SIRT1 (0.85) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8343583 | 0.86 | SIRT1 (0.85) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10049963 | 0.84 | MEN1 (0.79) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28519354 | 0.84 | KMT2A (0.72) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL28513871 | 0.84 | KMT2A (0.72) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL13863948 | 0.84 | KMT2A (0.74) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | THE GENERAL HOSPITAL CORPORATION | 2021-08-05 | — | — | US | disclosed |
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238140-A1 | Compounds for Targeting Cancer Stem Cells | G3BP1, G3BP2, HMGB2 | MEN1 2384/4885KMT2A 1524/4885NPC1 1728/4885 |
| US-20110178077-A1 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | MEN1 3685/4885KMT2A 4781/4885NPC1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.