Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | NPC1 | O15118 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.67 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259192 | 0.78 | MAPT (0.77) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL28058986 | 0.73 | NR1H4 (0.71) | RAB9ANPC1MAPK1KMT2AMEN1 | |
| SCHEMBL6841397 | 0.72 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL31261642 | 0.71 | LRRK2 (0.53) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL14757323 | 0.71 | NPC1 (0.79) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL24470594 | 0.71 | CASP3 (0.63) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL12010986 | 0.71 | RAB9A (0.80) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL28244529 | 0.70 | ALOX5 (0.67) | MAPK1CYP3A4 | |
| SCHEMBL23091167 | 0.69 | NPC1 (0.67) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL28857623 | 0.69 | LMNA (0.71) | SMN1; SMN2RAB9ANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-8785452-B2 | Anti-infective compounds | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
| US-20110178077-A1 | Anti-infective compounds | INSTITUT PASTEUR KOREA (KR) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178077-A1 | Anti-infective compounds | RABGGTB, ELANE, SERPINB1 | SMN1; SMN2 4839/4885RAB9A 1091/4885NPC1 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.