Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117922 | 0.84 | LMNA (0.63) | LMNASMN1; SMN2CYP11B2ALDH1A1KMT2A | |
| SCHEMBL12445148 | 0.80 | CYP11B2 (0.46) | SMN1; SMN2CYP11B2DYRK1ADYRK2DYRK1B | |
| SCHEMBL10876568 | 0.78 | CMA1 (0.56) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11082661 | 0.78 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11114523 | 0.77 | ALDH1A1 (0.54) | LMNAALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL807311 | 0.77 | TMEM97 (0.53) | LMNASMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL11142367 | 0.74 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL11110045 | 0.74 | CMA1 (0.54) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL12445146 | 0.74 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL26667208 | 0.73 | NPSR1 (0.50) | LMNASMN1; SMN2CYP11B2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053372-A1 | 5-HT RECEPTOR MODULATORS | CAMBRIDGE ENTERPRISE LIMITED | 2013-02-28 | — | — | US | disclosed |
| US-20130053372-A1 | 5-HT RECEPTOR MODULATORS | CAMBRIDGE ENTERPRISE LIMITED | 2013-02-28 | — | — | US | disclosed |
| WO-2011098776-A1 | 5-HT RECEPTOR MODULATORS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053372-A1 | 5-HT RECEPTOR MODULATORS | HTR1B, HTR5A, HTR1A | LMNA 3961/4885SMN1; SMN2 2528/4885CYP11B2 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.