Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417367 | 0.87 | ACHE (0.61) | ACHEEPHX1 | |
| SCHEMBL7781306 | 0.87 | ACHE (0.61) | ACHEEPHX1 | |
| SCHEMBL27712904 | 0.87 | ACHE (0.61) | ACHEEPHX1 | |
| SCHEMBL1023071 | 0.87 | ACHE (0.61) | ACHEEPHX1 | |
| SCHEMBL16486265 | 0.85 | ACHE (0.44) | ACHEMAPT | |
| SCHEMBL8811962 | 0.85 | ACHE (0.67) | ACHEEPHX2EPHX1 | |
| SCHEMBL7440478 | 0.85 | ACHE (0.67) | ACHEEPHX2EPHX1 | |
| SCHEMBL7570219 | 0.84 | ACHE (0.61) | ACHEEPHX1 | |
| SCHEMBL11492351 | 0.84 | ACHE (0.47) | ACHEEPHX2EPHX1 | |
| SCHEMBL15109213 | 0.84 | ACHE (0.47) | ACHEEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763995-B2 | Polymer conjugates of protegrin peptides | NEKTAR THERAPEUTICS (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160158311-A1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | NEKTAR THERAPEUTICS | 2016-06-09 | — | — | US | disclosed |
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158311-A1 | POLYMER CONJUGATES OF PROTEGRIN PEPTIDES | PSMG3, PSMB11, UBQLN1 | ACHE 4515/4885EPHX2 3396/4885EPHX1 3817/4885 |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | CALCR, CALCB, CALCA | ACHE 2086/4885EPHX2 835/4885EPHX1 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.