Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446378 | 0.89 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL14356056 | 0.79 | HSP90AA1 (0.37) | NQO2CYP19A1DRD2DRD1HSP90AA1 | |
| SCHEMBL16449681 | 0.78 | NQO2 (0.34) | NQO2CYP19A1BADDRD2DRD1 | |
| SCHEMBL29565955 | 0.76 | NQO2 (0.37) | NQO2CYP19A1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL697978 | 0.76 | HSP90AA1 (0.39) | NQO2CYP19A1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL29362227 | 0.76 | NQO2 (0.37) | NQO2CYP19A1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL698217 | 0.76 | NQO2 (0.37) | NQO2CYP19A1HSP90AA1HSP90AB1LMNA | |
| SCHEMBL27899 | 0.76 | ABCG2 (0.39) | BADDRD2DRD1HSP90AA1HSP90AB1 | |
| SCHEMBL29352284 | 0.76 | ABCG2 (0.39) | BADDRD2DRD1HSP90AA1HSP90AB1 | |
| SCHEMBL2076685 | 0.76 | ABCG2 (0.39) | BADDRD2DRD1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | BASF SE (DE) | 2018-07-05 | — | — | US | disclosed |
| US-9975837-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2018-05-22 | — | — | US | disclosed |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2018-03-01 | — | — | US | disclosed |
| WO-2016097242-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-8623621-B2 | Method for producing optically active 2-methyl-alkanols | BASF SE (DE) | 2014-01-07 | — | — | US | disclosed |
| US-8623621-B2 | Method for producing optically active 2-methyl-alkanols | BASF SE (DE) | 2014-01-07 | — | — | US | disclosed |
| US-7973198-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2011-07-05 | — | — | US | disclosed |
| US-7973198-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2011-07-05 | — | — | US | disclosed |
| US-20110045560-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-METHYL-ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2011-02-24 | — | — | US | disclosed |
| US-20110045560-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-METHYL-ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2011-02-24 | — | — | US | disclosed |
| US-7816107-B2 | Method for producing an optically active 2-methyl-alkane-1-ol from the corresponding 2-methylalk-2-en-1-al, comprising carbonyl-selective reduction, enantioselective hydration and lipase-catalyzed, stereoselective acylation in order to enrich the desired | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-19 | — | — | US | disclosed |
| US-7816107-B2 | Method for producing an optically active 2-methyl-alkane-1-ol from the corresponding 2-methylalk-2-en-1-al, comprising carbonyl-selective reduction, enantioselective hydration and lipase-catalyzed, stereoselective acylation in order to enrich the desired | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-19 | — | — | US | disclosed |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7709688-B2 | Method for the production of menthol | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20080139852-A1 | Method For The Production Of Menthol | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080108117-A1 | Method for Producing an Optically Active 2-Methyl-Alkane-1-Ol from the Corresponding 2-Methylalk-2-En-1-Al, Comprising Carbonyl-Selective Reduction, Enantioselective Hydration and Lipase-Catalyzed Stereoselective Acylation in Order to Enrich the Desired | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108117-A1 | Method for Producing an Optically Active 2-Methyl-Alkane-1-Ol from the Corresponding 2-Methylalk-2-En-1-Al, Comprising Carbonyl-Selective Reduction, Enantioselective Hydration and Lipase-Catalyzed Stereoselective Acylation in Order to Enrich the Desired | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | CAT, AOC1, CYCS | NQO2 469/4885CYP19A1 1014/4885BAD 2009/4885 |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | HMOX1, HMOX2, CBR1 | NQO2 1682/4885CYP19A1 837/4885BAD 1093/4885 |
| US-20080139852-A1 | Method For The Production Of Menthol | NISCH, CYP8B1, MSMO1 | NQO2 2472/4885CYP19A1 200/4885BAD 1141/4885 |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | CBR3, CBR1, HRH4 | NQO2 1031/4885CYP19A1 1259/4885BAD 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.