Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076685 | 1.00 | ABCG2 (0.39) | ABCG2CYP3A4TDP1TXNRD1TXNRD3 | |
| SCHEMBL29352284 | 1.00 | ABCG2 (0.39) | ABCG2CYP3A4TDP1TXNRD1TXNRD3 | |
| SCHEMBL6904608 | 0.98 | ABCG2 (0.38) | ABCG2CYP3A4TDP1TXNRD1TXNRD3 | |
| SCHEMBL16449681 | 0.91 | NQO2 (0.34) | ABCG2CYP3A4TDP1TXNRD1TXNRD3 | |
| Acetic Acid SCHEMBL29761322 | 0.91 | NPC1 (0.35) | CYP3A4TDP1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL17758851 | 0.89 | DRD1 (0.32) | ABCG2TXNRD1TXNRD3TXNRD2CYP1A2 | |
| SCHEMBL13695077 | 0.89 | AOC3 (0.37) | ABCG2TDP1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL29365010 | 0.86 | ITGB2 (0.39) | CYP3A4TDP1DRD1MAOBPKM | |
| SCHEMBL1203836 | 0.86 | ITGB2 (0.39) | CYP3A4TDP1DRD1MAOBPKM | |
| SCHEMBL5684662 | 0.85 | ABCG2 (0.38) | ABCG2CYP3A4TDP1TXNRD1TXNRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710422-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-07 | — | — | EP | claimed |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | INFINITY PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | claimed |
| WO-2023114926-A1 | GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2023-06-22 | — | — | WO | claimed |
| US-20230192586-A1 | GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2023-06-22 | — | — | US | claimed |
| CN-115746037-A | Synthetic method of alpha-halogenated borate compound and product thereof | 同济大学 | 2023-03-07 | — | — | CN | claimed |
| US-11530177-B2 | Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2022-12-20 | — | — | US | claimed |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | Química Sintética, S.A. (ES) | 2022-10-11 | — | — | US | claimed |
| EP-2964384-B1 | AQUEOUS HYDROGENATION REACTIONS USING WATER-INSOLUBLE RUTHENIUM CATALYST COMPOSITION | DUDECHEM GMBH (DE) | 2022-05-04 | — | — | EP | claimed |
| US-20220064375-A1 | Polyesters and Polyketoesters from Carbonylative Terpolymerization of enols, Methods to Produce, Blends, and Articles Therefrom | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2022-03-03 | — | — | US | claimed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | claimed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | claimed |
| US-8563752-B2 | Process for the production of carnitine by cycloaddition | LONZA LTD. (CH) | 2013-10-22 | — | — | US | claimed |
| EP-2634172-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2013-09-04 | — | — | EP | claimed |
| US-20130217893-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-08-22 | — | — | US | claimed |
| EP-2531486-A2 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB Pharma GmbH (DE) | 2012-12-12 | — | — | EP | claimed |
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | UCB PHARMA, S.A. (BE) | 2012-11-29 | — | — | US | claimed |
| WO-2011095539-A2 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB PHARMA GMBH (DE) | 2011-08-11 | — | — | WO | claimed |
| US-7902110-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | claimed |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | MERCK SHARP & DOHME LLC | 2008-03-06 | — | — | US | claimed |
| EP-1650207-B1 | Process for producing optically active 3-quinuclidinols | TAKASAGO PERFUMERY CO LTD (JP) | 2007-06-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | AADAT, AANAT, ASNS | ABCG2 1997/4885CYP3A4 101/4885TDP1 2264/4885 |
| US-20080058522-A1 | Process For The Preparation Of Enantiomerically Enriched Beta Amino Acid Derivatives | ATIC, SLC1A5, SLC7A1 | ABCG2 2335/4885CYP3A4 2844/4885TDP1 4047/4885 |
| US-20130217893-A1 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE | PTGS1, PTGER1, HPD | ABCG2 3102/4885CYP3A4 49/4885TDP1 1760/4885 |
| US-11530177-B2 | Formation of α,β-unsaturated carboxylic acids and salts thereof from metalalactones and anionic polyelectrolytes | ME1, ACSL1, ALOX12 | ABCG2 3455/4885CYP3A4 2100/4885TDP1 3846/4885 |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | S1PR1, S1PR4, S1PR3 | ABCG2 2639/4885CYP3A4 1653/4885TDP1 2234/4885 |
| US-20230192586-A1 | GAS PHASE PROCESS FOR ACRYLATE PRODUCTION FROM ETHYLENE AND CARBON DIOXIDE | MSMO1, ALOX15, ALOX12 | ABCG2 4434/4885CYP3A4 1550/4885TDP1 2245/4885 |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | ABCG2 215/4885CYP3A4 288/4885TDP1 344/4885 |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | S1PR1, S1PR4, S1PR3 | ABCG2 2639/4885CYP3A4 1653/4885TDP1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.