Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239199 | 0.92 | TDP1 (0.65) | TDP1CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL123838 | 0.87 | TSHR (0.61) | ENPP2DAOTSHRPRSS1PRSS2 | |
| SCHEMBL1244841 | 0.86 | CYP4F2 (0.49) | TDP1CYP4F2CYP4A11ENPP2DAO | |
| SCHEMBL15250083 | 0.85 | TDP1 (0.56) | TDP1CYP4F2CYP4A11KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL14334287 | 0.84 | ENPP2 (0.58) | ENPP2DAOTSHRPRSS1PRSS2 | |
| SCHEMBL9454318 | 0.83 | TSHR (0.59) | TDP1CYP4F2CYP4A11ENPP2DAO | |
| SCHEMBL10922837 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11ENPP2DAOTSHR | |
| SCHEMBL23120606 | 0.81 | ENPP2 (0.56) | TDP1CYP4F2CYP4A11ENPP2KDM4E | |
| SCHEMBL3812842 | 0.81 | TDP1 (0.52) | TDP1CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL1247008 | 0.81 | CYP4F2 (0.55) | TDP1CYP4F2CYP4A11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906969-A1 | ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF | East China University of Science and Technology (CN) | 2021-11-10 | — | — | EP | disclosed |
| US-11059941-B2 | Methods for preparing materials from polyaromatic heavy feedstocks | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20190315912-A1 | METHODS FOR PREPARING MATERIALS FROM POLYAROMATIC HEAVY FEEDSTOCKS | EXXONMOBIL RES & ENG CO (US) | 2019-10-17 | — | — | US | disclosed |
| US-10173209-B2 | Complex catalysts based on amino-phosphine ligands for hydrogenation and dehydrogenation processes | GOUSSEV DMITRI (CA) | 2019-01-08 | — | — | US | disclosed |
| US-20170174833-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170073298-A1 | CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES | GOUSSEV DMITRI (CA) | 2017-03-16 | — | — | US | disclosed |
| US-20160264726-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-09-15 | — | — | US | disclosed |
| EP-3062827-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | Bristol-Myers Squibb Company (US) | 2016-09-07 | — | — | EP | disclosed |
| US-9353216-B2 | High-fluidity polycarbonate copolymer, process for production highly polymerized aromatic polycarbonate resin and aromatic polycarbonate compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-05-31 | — | — | US | disclosed |
| WO-2015066456-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-07 | — | — | WO | disclosed |
| US-8148373-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |
| EP-2242759-A1 | COMPOUNDS | AstraZeneca AB (SE) | 2010-10-27 | — | — | EP | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
| WO-2009098448-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009098448-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10173209-B2 | Complex catalysts based on amino-phosphine ligands for hydrogenation and dehydrogenation processes | PWWP2B, FASN, ELOVL6 | TDP1 4565/4885CYP4F2 737/4885CYP4A11 933/4885 |
| US-20170073298-A1 | CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES | ACSL3, GLUL, FASN | TDP1 4705/4885CYP4F2 301/4885CYP4A11 203/4885 |
| US-20090298807-A1 | Compounds | PKD1, SLC10A1, ABCB11 | TDP1 4473/4885CYP4F2 69/4885CYP4A11 37/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | TDP1 4748/4885CYP4F2 348/4885CYP4A11 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.