Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264182 | 0.94 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 | |
| SCHEMBL12457026 | 0.86 | MMP2 (0.40) | SMN1; SMN2MMP2MMP9MMP3MMP8 | |
| SCHEMBL13889219 | 0.85 | NAMPT (0.33) | MMP2MMP9MMP3KDM4EMMP8 | |
| SCHEMBL271195 | 0.83 | MMP2 (0.39) | SMN1; SMN2MMP2MMP9MMP3MMP8 | |
| SCHEMBL13889220 | 0.81 | MMP2 (0.40) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 | |
| SCHEMBL300244 | 0.80 | MEN1 (0.52) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 | |
| SCHEMBL265660 | 0.80 | MMP2 (0.41) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 | |
| SCHEMBL265305 | 0.79 | LMNA (0.36) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 | |
| SCHEMBL265249 | 0.77 | MMP2 (0.40) | SMN1; SMN2MMP2MMP9MMP3MMP8 | |
| SCHEMBL301236 | 0.75 | MMP2 (0.43) | ALDH1A1SMN1; SMN2MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205571-B1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-31 | — | — | EP | disclosed |