Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264182 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL300808 | 0.81 | SMN1; SMN2 (0.47) | MMP2MMP9MMP3HDAC3HDAC4 | |
| SCHEMBL12456100 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL271378 | 0.77 | MMP2 (0.54) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL300822 | 0.77 | MMP2 (0.53) | MMP2MMP9MMP3EPHX2HDAC3 | |
| SCHEMBL300824 | 0.76 | MMP2 (0.70) | KMT2AMMP2MMP9MMP3HDAC3 | |
| SCHEMBL12456454 | 0.76 | MMP2 (0.53) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL11143027 | 0.75 | MMP9 (0.68) | KMT2AMMP2MMP9MMP3HDAC3 | |
| SCHEMBL271112 | 0.75 | MMP2 (0.54) | MEN1KMT2AMMP2MMP9MMP3 | |
| SCHEMBL300807 | 0.73 | MMP2 (0.49) | MEN1KMT2AMMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| EP-2205571-B1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-31 | — | — | EP | disclosed |
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | PGM2, CYP4F2, CYP3A7 | MEN1 4526/4885KMT2A 1627/4885MMP2 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.