Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465803 | 0.77 | RARA (0.44) | SSTR5PTGS1PTGS2 | |
| SCHEMBL3819800 | 0.69 | RXRA (0.49) | — | |
| SCHEMBL12465698 | 0.68 | PTGS2 (0.46) | SSTR5PTGS1PTGS2 | |
| SCHEMBL17344743 | 0.67 | — | — | |
| SCHEMBL6992997 | 0.67 | CES2 (0.39) | — | |
| SCHEMBL12465678 | 0.65 | SSTR5 (0.33) | SSTR5 | |
| SCHEMBL16600784 | 0.64 | ERN1 (0.39) | — | |
| SCHEMBL2464415 | 0.63 | TUBB1 (0.38) | — | |
| SCHEMBL16259587 | 0.63 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL671842 | 0.62 | RARB (0.33) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670744-A1 | PYRROLE DERIVATIVES USED AS MODULATORS OF ALPHA7 NACHR | Lupin Limited (IN) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012104782-A1 | PYRROLE DERIVATIVES USED AS MODULATORS OF ALPHA7 NACHR | LUPIN LIMITED (IN) | 2012-08-09 | — | — | WO | disclosed |