Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120216 | 0.83 | P4HB (0.38) | PTPN1PDE4DABCB1IDH1UGT1A1 | |
| SCHEMBL29198614 | 0.76 | KDM4E (0.50) | PTPN1PDE4DABCB1IDH1UGT1A1 | |
| SCHEMBL2311990 | 0.71 | CA12 (0.56) | PTPN1ABCB1IDH1UGT1A1DPP4 | |
| SCHEMBL20958247 | 0.70 | ESR1 (0.40) | PTPN1PDE4DABCB1IDH1UGT1A1 | |
| SCHEMBL1135764 | 0.70 | ALDH1A1 (0.58) | PTPN1PDE4DABCB1IDH1UGT1A1 | |
| SCHEMBL910546 | 0.68 | APP (0.43) | ALDH1A1LMNAALOX15HSD17B10POLB | |
| SCHEMBL7191193 | 0.67 | PTPN1 (0.44) | PTPN1PDE4DABCB1IDH1UGT1A1 | |
| SCHEMBL3892471 | 0.67 | — | — | |
| SCHEMBL30335079 | 0.65 | PTPN1 (0.63) | PTPN1ABCB1IDH1UGT1A1DPP4 | |
| SCHEMBL6743389 | 0.63 | KDM4E (0.41) | LMNAHSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045517-B2 | Glycosylated aminocoumarins and methods of preparing and uses of same | UNIVERSITY COLLEGE LONDON (GB) | 2015-06-02 | — | — | US | disclosed |
| EP-2627661-B1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | UNIV LONDON (GB) | 2015-03-18 | — | — | EP | disclosed |
| US-20130274213-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | UNIVERSITY COLLEGE LONDON (GB) | 2013-10-17 | — | — | US | disclosed |
| EP-2627661-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | University College London (GB) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049521-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274213-A1 | GLYCOSYLATED AMINOCOUMARINS AND METHODS OF PREPARING AND USES OF SAME | GALE, UGGT1, FUT6 | PTPN1 3594/4885PDE4D 3321/4885ABCB1 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.