Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246072 | 0.80 | CXCR1 (0.31) | — | |
| SCHEMBL11092340 | 0.78 | HSD17B10 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7160560 | 0.78 | HSD17B10 (0.50) | PTGS2CA1CA2HPGDHSD17B10 | |
| SCHEMBL7152669 | 0.78 | GAA (0.47) | KDM4EPTGS2CA1CA2GAA | |
| SCHEMBL7149064 | 0.78 | ALOX15 (0.50) | APPKDM4ECA1CA2POLB | |
| SCHEMBL6743389 | 0.78 | KDM4E (0.41) | KDM4ECA6CA9CA14HSD17B10 | |
| SCHEMBL18130059 | 0.78 | APP (0.48) | APPKDM4EPTGS2CA1CA2 | |
| SCHEMBL4678492 | 0.77 | ALOX15 (0.55) | KDM4ECA1CA2CA4CA6 | |
| SCHEMBL217250 | 0.74 | CA12 (0.52) | APPKDM4ECA2CA6MAPT | |
| SCHEMBL2338290 | 0.74 | APP (0.43) | APPKDM4EPTGS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119068-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | OHIO STATE INNOVATION FOUNDATION | 2023-04-20 | — | — | US | claimed |
| WO-2021163679-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | OHIO STATE INNOVATION FOUNDATION (US) | 2021-08-19 | — | — | WO | claimed |
| CN-106478968-B | A kind of preparation method of nanometer of Kapton | 陕西科技大学 | 2019-06-28 | — | — | CN | claimed |
| CN-109748780-A | The synthetic method of a kind of four poly- benzyl compounds | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | claimed |
| CN-109734759-A | A kind of catalpol derivatives and its application | 上海中医药大学 | 2019-05-10 | — | — | CN | claimed |
| CN-106810554-B | A kind of preparation method of Tadalafei compound | 山东罗欣药业集团恒欣药业有限公司 | 2019-02-15 | — | — | CN | claimed |
| US-8974837-B2 | Pharmaceutical composition comprising an extract of Pseudolysimachion longifolium and the catalpol derivatives isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2015-03-10 | — | — | US | claimed |
| US-8455541-B2 | Pharmaceutical composition comprising an extract of pseudolysimachion longifolium and the catalpol derivatives isolated therefrom having antiinflammatory, antiallergic and antiasthmatic activity | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-06-04 | — | — | US | claimed |
| US-20120183632-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-07-19 | — | — | US | claimed |
| US-20120184499-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-07-19 | — | — | US | claimed |
| WO-1998002741-A9 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | — | 1998-05-22 | — | — | WO | claimed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | claimed |
| EP-0748219-A1 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | Sugen, Inc. (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | claimed |
| US-5504076-A | Cephalosporin compounds | PFIZER INC. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1995021613-A1 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | SUGEN, INC. (US) | 1995-08-17 | — | — | WO | claimed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | claimed |
| EP-0416814-A2 | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1991-03-13 | — | — | EP | claimed |
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | claimed |
| EP-0075629-A1 | Imidazole derivatives, their preparation, and their pharmaceutical compositions | Sumitomo Chemical Industries Ltd. (JP) | 1983-04-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184499-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | IL4, IL5, MMP13 | APP 4320/4885KDM4E 560/4885PTGS2 514/4885 |
| US-20230119068-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | HCCS, PPOX, RNGTT | APP 3271/4885KDM4E 2442/4885PTGS2 658/4885 |
| US-20120183632-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN EXTRACT OF PSEUDOLYSIMACHION LONGIFOLIUM AND THE CATALPOL DERIVATIVES ISOLATED THEREFROM HAVING ANTIINFLAMMATORY, ANTIALLERGIC AND ANTIASTHMATIC ACTIVITY | IL4, IL5, MMP13 | APP 4320/4885KDM4E 560/4885PTGS2 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.