Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469038 | 0.95 | PARP1 (0.40) | PRKAA2PRKAA1ALDH1A1BTKPARP1 | |
| SCHEMBL12469573 | 0.89 | ALPL (0.40) | ALDH1A1BTK | |
| SCHEMBL12469508 | 0.86 | BTK (0.40) | BTK | |
| SCHEMBL12469295 | 0.85 | SMYD2 (0.41) | ALDH1A1KDM4ENAMPT | |
| SCHEMBL12469562 | 0.83 | BTK (0.42) | BTK | |
| SCHEMBL12469581 | 0.83 | CACNA1G (0.43) | PARP1 | |
| SCHEMBL12469678 | 0.83 | KMT2A (0.50) | ALDH1A1KDM4E | |
| SCHEMBL12469505 | 0.82 | BTK (0.41) | BTK | |
| SCHEMBL12469512 | 0.81 | CRBN (0.41) | ALDH1A1BTKDYRK1A | |
| SCHEMBL12469481 | 0.81 | ALOX5 (0.40) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |