Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 11/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469505 | 0.89 | BTK (0.41) | BTKKDRFLT3CRBNMAPK14 | |
| SCHEMBL12469562 | 0.89 | BTK (0.42) | BTKKDRFLT3CRBN | |
| SCHEMBL12469508 | 0.86 | BTK (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469765 | 0.84 | AURKA (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469512 | 0.84 | CRBN (0.41) | BTKCRBN | |
| SCHEMBL12469573 | 0.83 | ALPL (0.40) | BTKKDRFLT3MAPK14 | |
| SCHEMBL12469038 | 0.82 | PARP1 (0.40) | BTKKDRMAPK14 | |
| SCHEMBL10048588 | 0.82 | BTK (0.44) | BTKKDRFLT3MAPK14 | |
| SCHEMBL12469540 | 0.81 | L3MBTL1 (0.40) | BTK | |
| SCHEMBL12469581 | 0.81 | CACNA1G (0.43) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |