Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 8/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469562 | 0.87 | BTK (0.42) | CRBNBTKALOX5APFEN1 | |
| SCHEMBL12469573 | 0.85 | ALPL (0.40) | BTKALOX5APFEN1ALDH1A1 | |
| SCHEMBL12469505 | 0.85 | BTK (0.41) | CRBNBTK | |
| SCHEMBL12469765 | 0.84 | AURKA (0.40) | BTK | |
| SCHEMBL12469508 | 0.84 | BTK (0.40) | BTK | |
| SCHEMBL12469481 | 0.84 | ALOX5 (0.40) | CRBNBTK | |
| SCHEMBL12469038 | 0.82 | PARP1 (0.40) | BTKACKR3ALDH1A1 | |
| SCHEMBL12469581 | 0.81 | CACNA1G (0.43) | — | |
| SCHEMBL12469540 | 0.81 | L3MBTL1 (0.40) | BTKALDH1A1DYRK1A | |
| SCHEMBL12469295 | 0.80 | SMYD2 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |