Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469540 | 0.95 | L3MBTL1 (0.40) | PARP1BTKALDH1A1PRKAA2PRKAA1 | |
| SCHEMBL12469573 | 0.89 | ALPL (0.40) | BTKHTTPDGFRBKDRKIT | |
| SCHEMBL12469508 | 0.88 | BTK (0.40) | BTKKDR | |
| SCHEMBL12469562 | 0.85 | BTK (0.42) | BTKKDR | |
| SCHEMBL12469581 | 0.84 | CACNA1G (0.43) | PARP1PDGFRBKDRKITFGFR1 | |
| SCHEMBL12469505 | 0.83 | BTK (0.41) | BTKKDRMAPK14 | |
| SCHEMBL12469295 | 0.83 | SMYD2 (0.41) | PDGFRBKDRKITALDH1A1 | |
| SCHEMBL12469481 | 0.82 | ALOX5 (0.40) | BTKKDRMAPK14 | |
| SCHEMBL12469512 | 0.82 | CRBN (0.41) | ACKR3BTKALDH1A1 | |
| SCHEMBL12469574 | 0.82 | BCL3 (0.49) | PARP1SMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |