Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.44 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.44 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728073 | 0.86 | HSD11B1 (0.44) | HSD11B1OPRM1GRM5 | |
| SCHEMBL11963480 | 0.82 | MEN1 (0.42) | HSD11B1KMT2AOPRM1MEN1ALDH1A1 | |
| SCHEMBL9052325 | 0.81 | OPRM1 (0.58) | HSD11B1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL25413622 | 0.81 | HSD11B1 (0.42) | HSD11B1KMT2AOPRM1MEN1AKR1C1 | |
| SCHEMBL5807539 | 0.80 | FASN (0.47) | — | |
| SCHEMBL795975 | 0.79 | ALDH1A1 (0.56) | HSD11B1KMT2AOPRM1MEN1ALDH1A1 | |
| SCHEMBL27645813 | 0.79 | SCD5 (0.42) | HSD11B1SCD5KMT2ATET3FBXL19 | |
| SCHEMBL237234 | 0.78 | TSHR (0.56) | SCD5KMT2AMEN1TSHR | |
| SCHEMBL10322683 | 0.78 | OPRM1 (0.47) | HSD11B1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL23779147 | 0.78 | KMT2A (0.69) | HSD11B1KMT2ATET3FBXL19CXXC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2627651-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |