Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 4/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469678 | 0.95 | KMT2A (0.50) | BCL3KMT2ALMNASMN1; SMN2 | |
| SCHEMBL12469581 | 0.93 | CACNA1G (0.43) | BCL3PARP1EPHX2 | |
| SCHEMBL12469295 | 0.88 | SMYD2 (0.41) | KMT2A | |
| SCHEMBL12469573 | 0.85 | ALPL (0.40) | MAPK14 | |
| SCHEMBL12469508 | 0.82 | BTK (0.40) | — | |
| SCHEMBL12469038 | 0.82 | PARP1 (0.40) | PARP1MAPK14SMN1; SMN2 | |
| SCHEMBL1292531 | 0.82 | BCL3 (0.59) | BCL3KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL12469540 | 0.81 | L3MBTL1 (0.40) | PARP1 | |
| SCHEMBL12469562 | 0.80 | BTK (0.42) | — | |
| SCHEMBL12469512 | 0.79 | CRBN (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |