Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1570242 | 0.69 | KDM4E (0.50) | PKMKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL12475149 | 0.69 | CYP2A13 (0.35) | CYP2A13MEN1KMT2A | |
| SCHEMBL455192 | 0.69 | — | — | |
| SCHEMBL1476654 | 0.68 | ALDH1A1 (0.40) | GAAKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL12475151 | 0.68 | L3MBTL1 (0.51) | CYP2A13KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4763981 | 0.67 | SMN1; SMN2 (0.39) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2183711 | 0.66 | ALDH1A1 (0.51) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16462153 | 0.66 | CYP2A13 (0.61) | CYP2A13GAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6235367 | 0.66 | PKM (0.41) | PKMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3831752 | 0.65 | MCL1 (0.41) | PKMKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110603-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | WO | disclosed |