Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478249 | 0.73 | TGM2 (0.36) | — | |
| SCHEMBL12478166 | 0.73 | ALDH1A1 (0.51) | — | |
| SCHEMBL12686308 | 0.70 | TGM2 (0.40) | — | |
| SCHEMBL12686425 | 0.67 | S100A4 (0.42) | BRD4 | |
| SCHEMBL12479266 | 0.67 | S100A4 (0.42) | BRD4 | |
| SCHEMBL12478483 | 0.64 | KDM4E (0.32) | — | |
| SCHEMBL12478389 | 0.63 | S100A4 (0.42) | — | |
| SCHEMBL12478951 | 0.61 | PTGS2 (0.45) | — | |
| SCHEMBL12479159 | 0.61 | GRM5 (0.48) | — | |
| SCHEMBL13742830 | 0.60 | CA1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012110860-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-08-23 | — | — | WO | disclosed |
| WO-2012110860-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-08-23 | — | — | WO | disclosed |