SCHEMBL124835

SCHEMBL124835

c1ccc2c(-c3ccc(-c4c5ccccc5c(-c5cccc6c5sc5ccccc56)c5ccccc45)cc3)cccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
PARP14 Q460N5 1/20 0.41
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
F9 P00740 1/20 0.38
GPR3 P46089 1/20 0.37
PRKDC P78527 4/20 0.35
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
PPARD Q03181 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125824 0.95 ALOX5 (0.55) ALOX5CA12CA1CA2CA9
SCHEMBL27301562 0.94 ALOX5 (0.48) ALOX5CA12CA1CA2CA9
SCHEMBL17539985 0.94 ALOX5 (0.54) ALOX5CA12CA1CA2CA9
SCHEMBL12768005 0.93 ALOX5 (0.47) ALOX5CA12CA1CA2CA9
SCHEMBL17944307 0.93 ALOX5 (0.46) ALOX5CA12CA1CA2CA9
SCHEMBL21450758 0.91 ALOX5 (0.58) ALOX5PARP14GPR3PRKDCPIK3CD
SCHEMBL23428256 0.90 ALOX5 (0.44) ALOX5CA12CA1CA2CA9
SCHEMBL23746951 0.90 ALOX5 (0.44) ALOX5CA12CA1CA2CA9
SCHEMBL22180820 0.90 ALOX5 (0.45) ALOX5CA12CA1CA2CA9
SCHEMBL23427851 0.90 CA12 (0.41) ALOX5CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 US disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 US disclosed
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230301175-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
WO-2023172111-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-09-14 WO disclosed
WO-2023172110-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-09-14 WO disclosed
US-11685751-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-11685751-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2023-06-27 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 ALOX5 3902/4885CA12 1764/4885CA1 1830/4885
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 ALOX5 3494/4885CA12 3085/4885CA1 2549/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 ALOX5 4030/4885CA12 3354/4885CA1 2843/4885
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND CYP1A1, AOX1, CYP1B1 ALOX5 547/4885CA12 1977/4885CA1 2963/4885
US-11780856-B2 Compound and organic light-emitting device comprising same CRY1, CRY2, LEF1 ALOX5 887/4885CA12 1937/4885CA1 2199/4885
US-11685751-B2 Compound and organic light-emitting element comprising same CRY1, CRY2, LEF1 ALOX5 1032/4885CA12 1416/4885CA1 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.