SCHEMBL12486646

SCHEMBL12486646

Cc1cc(C)cc(-c2ccc3c(Br)cccc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.49
GRM5 P41594 1/20 0.39
KCNH2 Q12809 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
NR1I3 Q14994 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
TSHR P16473 2/20 0.34
TDO2 P48775 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30052647 1.00 BACE1 (0.49) BACE1GRM5KCNH2SMN1; SMN2LMNA
SCHEMBL4436178 0.83 CYP1A2 (0.43) BACE1SMN1; SMN2ADORA2AADORA1NR1I3
SCHEMBL29531209 0.83 CYP1A2 (0.43) BACE1SMN1; SMN2ADORA2AADORA1NR1I3
SCHEMBL10318960 0.81 AR (0.40) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL29769817 0.81 AR (0.40) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL10078860 0.81 MBNL1 (0.36) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL13731592 0.79 ADORA2A (0.35) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL17453340 0.79 ACACA (0.46) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL12485868 0.79 ADORA2A (0.35) SMN1; SMN2LMNAHPGDADORA2AADORA1
SCHEMBL24756251 0.78 LMNA (0.37) SMN1; SMN2LMNAHPGDADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3968404-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2026-04-01 EP disclosed
US-20240397810-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-11-28 US disclosed
US-12082485-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-11674080-B2 Transition metal complex, polymer, mixture, formulation and use thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2023-06-13 US disclosed
US-11674080-B2 Transition metal complex, polymer, mixture, formulation and use thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2023-06-13 US disclosed
CN-115304647-A Organic electroluminescent material and device 环球展览公司 2022-11-08 CN disclosed
CN-115216291-A Organic electroluminescent material and device 环球展览公司 2022-10-21 CN disclosed
US-20220246867-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-08-04 US disclosed
US-11404651-B2 Transition metal complex material and application thereof in electronic devices GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-08-02 US disclosed
US-11342516-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-24 US disclosed
US-20160190486-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-06-30 US disclosed
US-20160190486-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-06-30 US disclosed
US-20160190485-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-06-30 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed
EP-3007244-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-04-13 EP disclosed
EP-3007244-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-04-13 EP disclosed
WO-2012148511-A1 5-SUBSTITUTED 2-PHENYLQUINOLINE COMPLEXES MATERIALS FOR LIGHT EMITTING DIODE UNIVERSAL DISPLAY CORPORATION (US) 2012-11-01 WO disclosed
WO-2012116243-A1 GERMANIUM-CONTAINING RED EMITTER MATERIALS FOR ORGANIC LIGHT EMITTING DIODE UNIVERSAL DISPLAY CORPORATION (US) 2012-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220246867-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG BACE1 2754/4885GRM5 3953/4885KCNH2 439/4885
US-11342516-B2 Organic electroluminescent materials and devices ORC3, OCIAD1, ICOSLG BACE1 2754/4885GRM5 3953/4885KCNH2 439/4885
US-12082485-B2 Organic electroluminescent materials and devices ORC3, OCIAD1, ICOSLG BACE1 2754/4885GRM5 3953/4885KCNH2 439/4885
US-11674080-B2 Transition metal complex, polymer, mixture, formulation and use thereof OPRD1, OCIAD1, OCIAD2 BACE1 3786/4885GRM5 1282/4885KCNH2 620/4885
US-20160190485-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, LEF1, ORC3 BACE1 2421/4885GRM5 3313/4885KCNH2 111/4885
US-20240397810-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG BACE1 2754/4885GRM5 3953/4885KCNH2 439/4885
US-11404651-B2 Transition metal complex material and application thereof in electronic devices OCIAD1, OCIAD2, EED BACE1 1803/4885GRM5 2150/4885KCNH2 1329/4885
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, FARS2, FARSA BACE1 3109/4885GRM5 3543/4885KCNH2 173/4885
US-20160190486-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LEF1, TYR, YBX1 BACE1 2616/4885GRM5 3490/4885KCNH2 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.