SCHEMBL10078860

SCHEMBL10078860

Cc1cc(C)cc(-c2ccc3c(F)cccc3n2)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MBNL1 Q9NR56 1/20 0.36
AR P10275 2/20 0.36
PDE10A Q9Y233 1/20 0.36
ADORA2A P29274 2/20 0.36
ADORA1 P30542 1/20 0.36
NR1I3 Q14994 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDO2 P48775 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4438398 0.89 BCHE (0.44) NR1I3KMT2ANPC1RAB9ATDP1
SCHEMBL29531209 0.83 CYP1A2 (0.43) ARPDE10AADORA2AADORA1NR1I3
SCHEMBL4436178 0.83 CYP1A2 (0.43) ARPDE10AADORA2AADORA1NR1I3
SCHEMBL24796159 0.82 LMNA (0.45) PDE10AADORA2AKMT2ATDP1THRB
SCHEMBL13658460 0.81 RAB9A (0.50) ARPDE10AKMT2ANPC1RAB9A
SCHEMBL12486646 0.81 BACE1 (0.49) ADORA2AADORA1NR1I3KMT2ANPC1
SCHEMBL29769817 0.81 AR (0.40) ARADORA2AADORA1NR1I3KMT2A
SCHEMBL13399632 0.81 PDE10A (0.38) ARPDE10ANPC1RAB9ASMN1; SMN2
SCHEMBL10318960 0.81 AR (0.40) ARADORA2AADORA1NR1I3KMT2A
SCHEMBL30052647 0.81 BACE1 (0.49) ADORA2AADORA1NR1I3KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 US disclosed
US-10230060-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-12 US disclosed
EP-3327100-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2018-05-30 EP disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 US disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 US disclosed
US-9911930-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-06 US disclosed
US-20130248832-A1 Phosphorescent Materials UNIVERSAL DISPLAY CORPORATION 2013-09-26 US disclosed
US-20130248832-A1 Phosphorescent Materials UNIVERSAL DISPLAY CORPORATION 2013-09-26 US disclosed
EP-2121871-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2013-08-14 EP disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 US disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 MBNL1 4181/4885AR 3745/4885PDE10A 2790/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB MBNL1 154/4885AR 3225/4885PDE10A 3440/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 MBNL1 2972/4885AR 2404/4885PDE10A 4426/4885
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, ICMT MBNL1 744/4885AR 3103/4885PDE10A 2659/4885
US-10230060-B2 Organic electroluminescent materials and devices RUVBL2, OR10J3, EML4 MBNL1 1306/4885AR 2303/4885PDE10A 4564/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 MBNL1 3201/4885AR 1521/4885PDE10A 4386/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN MBNL1 811/4885AR 3107/4885PDE10A 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.