Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018338 | 0.90 | CES2 (0.56) | HPGDCHRM1MAPTKMT2AGAA | |
| SCHEMBL13875347 | 0.89 | HPGD (0.51) | HPGDCHRM1MAPTPOLBKDM4E | |
| SCHEMBL12489727 | 0.82 | HPGD (0.62) | HPGDPOLBKMT2AGAACYP2C9 | |
| SCHEMBL19380443 | 0.82 | PHGDH (0.66) | HPGDCHRM1MAPTPOLBKDM4E | |
| SCHEMBL12018348 | 0.82 | CES2 (0.47) | HPGDCHRM1MAPTPOLBKMT2A | |
| SCHEMBL5564719 | 0.81 | HPGD (0.66) | HPGDPOLBKMT2AGAACYP2C9 | |
| SCHEMBL4143496 | 0.81 | POLB (0.80) | HPGDPOLBKMT2AGRM5L3MBTL1 | |
| SCHEMBL8382619 | 0.81 | CYP2C19 (0.51) | HPGDCHRM1MAPTKMT2AL3MBTL1 | |
| SCHEMBL28919752 | 0.80 | MAPT (0.63) | MAPTPOLBKMT2ATSHRCYP2C9 | |
| SCHEMBL13875346 | 0.79 | ACHE (0.70) | HPGDKMT2AGAAGRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017077550-A1 | A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-11 | — | — | WO | claimed |
| WO-2017077550-A1 | A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-11 | — | — | WO | disclosed |
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |