Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23244290 | 0.90 | ME2 (0.62) | MAPTLMNAUSP2TSHRMAPK1 | |
| SCHEMBL12018338 | 0.89 | CES2 (0.56) | MAPTUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL19357088 | 0.83 | PHGDH (0.69) | MAPTLMNAUSP2TSHRMAPK1 | |
| SCHEMBL8595777 | 0.81 | POLB (0.87) | MAPTLMNAUSP2TSHRMAPK1 | |
| SCHEMBL12489727 | 0.81 | HPGD (0.62) | LMNAUSP2MAPK1POLBMEN1 | |
| SCHEMBL8386522 | 0.80 | PHGDH (0.70) | MAPTLMNATSHRMEN1KMT2A | |
| SCHEMBL8566690 | 0.80 | HPGD (0.62) | MAPTTSHRPOLBKMT2ACYP2C9 | |
| SCHEMBL3180448 | 0.80 | ALDH1A1 (0.61) | MAPTLMNAUSP2TSHRMAPK1 | |
| SCHEMBL13589640 | 0.80 | MEN1 (0.67) | MAPTLMNAUSP2TSHRMAPK1 | |
| SCHEMBL5564719 | 0.79 | HPGD (0.66) | LMNAUSP2MAPK1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248458-B | Preparation method of alpha-carbonyl amide compound | 陕西省煤田地质集团有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113248458-A | Preparation method of alpha-carbonyl amide compound | 陕西省煤田地质集团有限公司 | 2021-08-13 | — | — | CN | disclosed |