SCHEMBL1249129

SCHEMBL1249129

FC(F)=C(F)Oc1ccccc1.O=S(=O)(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 1/20 0.43
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
PKM P14618 2/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
HTR6 P50406 1/20 0.41
HTR2A P28223 3/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
MMP12 P39900 1/20 0.40
MMP13 P45452 1/20 0.40
MMP14 P50281 1/20 0.40
BCL2L1 Q07817 1/20 0.40
MCL1 Q07820 1/20 0.40
HSD11B1 P28845 1/20 0.40
ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505805 0.84 PKM (0.57) HTTSMN1; SMN2PKMMAPTPOLB
SCHEMBL6635153 0.81 NSD2 (0.39) SMN1; SMN2MAPTELANEMEN1KMT2A
SCHEMBL12761969 0.80 HSD11B1 (0.50) PKMMAPTPOLBHSD11B1ELANE
SCHEMBL6635236 0.79 NSD2 (0.38) SMN1; SMN2MAPTMEN1ALDH1A1KMT2A
SCHEMBL2330129 0.78 LTA4H (0.41) MAPTALDH1A1ALOX15
SCHEMBL12834521 0.78 HSD11B1 (0.48) PKMMAPTPOLBHSD11B1ELANE
SCHEMBL12834507 0.78 HSD11B1 (0.48) PKMMAPTPOLBMMP1MMP2
SCHEMBL11980110 0.76 HTR6 (0.70) HTTSMN1; SMN2PKMMAPTHTR6
SCHEMBL7937274 0.76 HTR6 (0.70) HTTSMN1; SMN2PKMMAPTHTR6
SCHEMBL778229 0.76 HTR6 (0.70) HTTSMN1; SMN2PKMMAPTHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897693-B2 Proton conductive polymer electrolytes and fuel cells GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-03-01 US disclosed
US-7888433-B2 Sulfonated-polyperfluoro-cyclobutane-polyphenylene polymers for PEM fuel cell applications GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-02-15 US disclosed
US-20090281270-A1 SULFONATED-POLYPERFLUORO-CYCLOBUTANE-POLYPHENLENE POLYMERS FOR PEM FUEL CELL APPLICATIONS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed